WR Injuries | Davante Adams (Brixton) | | Illness | |
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| Brandon Aiyuk | | Knee - ACL + MCL (Injured Reserve) | |
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| David Bell | | Hip (Injured Reserve) | |
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| Braxton Berrios | | Knee - ACL (Injured Reserve) | |
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| Marquise Brown | | Shoulder (Injured Reserve) | |
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| Treylon Burks | | Knee (Injured Reserve) | |
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| Keon Coleman | | Wrist | |
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| Nico Collins (A.C.) | | Hamstring | |
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| Chris Conley | | Hamstring | |
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| Brandin Cooks | | Knee (Injured Reserve) | |
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| Amari Cooper (Thad) | | Wrist | |
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| Britain Covey | | Shoulder (Injured Reserve) | |
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| Jamison Crowder | | Calf (Injured Reserve) | |
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| Gabriel Davis | | Shoulder | |
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| Stefon Diggs | | Knee - ACL (Injured Reserve) | |
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| Colton Dowell | | Knee - ACL (PUP) | |
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| Grant DuBose | | Shoulder (Injured Reserve) | |
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| Mike Evans (Brixton) | | Hamstring | |
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| Simi Fehoko | | Elbow (Injured Reserve) | |
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| Bryce Ford-Wheaton | | Achilles | |
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| Jeff Foreman | | Knee (Injured Reserve) | |
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| Chris Godwin | | Ankle (Injured Reserve) | |
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| Antoine Green | | Concussion (Injured Reserve) | |
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| Deonte Harty | | Knee (Injured Reserve) | |
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| Jaaron Hayek | | Shoulder (Injured Reserve) | |
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| Tee Higgins (Brett) | | Quadriceps | |
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| Tyreek Hill (A.C.) | | Wrist | |
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| JaQuae Jackson | | Knee (Injured Reserve) | |
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| Van Jefferson Jr. | | Quadriceps | |
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| Jauan Jennings (Byron) | | Ankle | |
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| Kameron Johnson | | Ankle (Injured Reserve) | |
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| Charlie Jones | | Groin | |
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| Christian Kirk | | Collarbone (Injured Reserve) | |
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| Allen Lazard | | Chest (Injured Reserve) | |
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| Bub Means | | Ankle (Injured Reserve) | |
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| Darnell Mooney (Tim) | | Achilles | |
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| Skyy Moore | | Abdomen (Injured Reserve) | |
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| Rondale Moore | | Knee (Injured Reserve) | |
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| Chris Olave (Gregg) | | Concussion (Injured Reserve) | |
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| Gunner Olszewski | | Groin (Injured Reserve) | |
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| Josh Reynolds | | Finger | |
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| Rashee Rice | | Knee (Injured Reserve) | |
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| Brenden Rice | | Shoulder (Injured Reserve) | |
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| Marcus Riley | | Undisclosed (Injured Reserve) | |
|
| John Ross | | Undisclosed | |
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| Anthony Schwartz | | Knee (Injured Reserve) | |
|
| Rashid Shaheed | | Knee - Meniscus (Injured Reserve) | |
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| Darius Slayton | | Concussion | |
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| Shi Smith | | Suspension | |
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| Malik Taylor | | Undisclosed (Injured Reserve) | |
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| Adam Thielen | | Hamstring | |
|
| Brian Thomas Jr. (Brixton) | | Chest | |
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| Cody Thompson | | Shoulder | |
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| Tahj Washington | | Undisclosed (Injured Reserve) | |
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| Nsimba Webster | | Groin (Injured Reserve) | |
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| Roman Wilson | | Hamstring (Injured Reserve) | |
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| Cedrick Wilson | | Shoulder | |
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| Juwann Winfree | | Undisclosed (Injured Reserve) | |
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